Pulmonary hemorrhage in dengue: differential diagnosis with acute viral respiratory syndromes including COVID-19

ABSTRACT Clinical similarities among viral diseases become even more relevant considering the current scenario, especially in Brazil, where there is a high incidence of these diseases and overlapping seasonality. We report the case of a patient with acute clinical manifestations composed of predomin...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Leonardo Antonio Aguiar, Ana Carolina de Morais Oliveira-Scussel, Jerônimo Coelho de Menezes, Priscila Barbosa Idaló, Lara Élida Guazzeli de Freitas, Luzia Beatriz Ribeiro Zago, Cristina da Cunha Hueb Barata de Oliveira, Naiara Clemente Tavares, Edward José de Oliveira, Marcos Vinícius da Silva, Luciana de Almeida Silva Teixeira
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2022
Subjects:
Dengue
Pulmonary hemorrhage
Viral respiratory syndromes
SARS-COV-2
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946202264013
https://doaj.org/article/38d259c1869044d2bd990b7db8ab4f1c
Description
Summary:ABSTRACT Clinical similarities among viral diseases become even more relevant considering the current scenario, especially in Brazil, where there is a high incidence of these diseases and overlapping seasonality. We report the case of a patient with acute clinical manifestations composed of predominant respiratory symptoms and alveolar hemorrhage in which three etiologies (dengue, influenza and COVID-19) were investigated concomitantly. Only the diagnosis of dengue was confirmed. Then, the patient’s immunological profile in response to stimulation of mononuclear cells with dengue virus antigen was analyzed in an attempt to identify specific characteristics that could be associated with the clinical manifestation.

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