Seasonal dynamics of 25-hydroxyvitamin D and biogenic amines in the blood of apparently healthy women living in the city of Arkhangelsk

• Published in: Сибирский научный медицинский журнал
• Main Authors: V. A. Alikina, E. V. Tipisova, A. E. Elfimova, I. N Molodovskaya, V. N. Zyabisheva
• Format: Article in Journal/Newspaper
• Language: Russian
• Published: Russian Academy of Sciences, Siberian Branch Publishing House 2024
• Subjects: 25-hydroxyvitamin vitamin d; dopamine; serotonin; epinephrine; norepinephrine; photoperiodism; seasonal dynamics; arctic zone of the russian federation; Medicine; R; Arctic; Arkhangelsk
• Online Access: https://doi.org/10.18699/SSMJ20240408; https://doaj.org/article/37f359e96be14470a9baecf398b4c069

The aim of the study is to assess the seasonal supply of vitamin D and biogenic amines to practically healthy women of working age living in Arkhangelsk. Material and methods. The study sample included 20 practically healthy women aged 22–44 years, permanently residing in Arkhangelsk. The study was conducted over 4 seasons: during the period of increasing (March), maximum (June), decreasing (September) and minimum daylight hours (December). The concentration of 25-hydroxyvitamin D, serotonin, dopamine, adrenaline and noradrenaline in the blood were determined. Results. The annual dynamics of 25-hydroxyvitamin D level in the blood was established with its minimum content in the winter (December), followed by an increase in the vitamin concentration in the spring, the highest level during the period of maximum daylight hours (June) and a further decrease in the fall (September). During the period of minimum day length, the smallest proportion of people (15 %) with optimal 25-hydroxyvitamin D concentration is observed, while more than half of women have insufficient level, and a quarter have vitamin D deficiency. Serotonin level decreased from spring to winter. The peak of dopamine concentration was recorded in the summer; the minimum content was recorded in the autumn. The minimum concentration of adrenaline and noradrenaline is noted in the spring; the maximum levels are in the winter. Conclusions. The most critical season for 25-hydroxyvitamin D content in women blood is the minimum duration of daylight hours’ period (December), while the more favorable season can be attributed to the maximum duration period (June) and a decrease in the duration of daylight hours (September). The annual 25-hydroxyvitamin D dynamics and serotonin levels have similar features, and seasonal changes in the adrenaline and noradrenaline concentration are in the opposite direction.