Synergistic interactions in mixed-species biofilms of pathogenic bacteria from the respiratory tract

Introduction Mixed-species biofilms are involved in a wide variety of infections. We studied the synergistic interactions during dual-species biofilm formation among isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia. Methods Isolates were cultured as singl...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Maryam Varposhti, Fatemeh Entezari, Mohammad Mehdi Feizabadi
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2014
Subjects:
Chronic infection
Mixed-species biofilm
Synergy
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/0037-8682-0262-2013
https://doaj.org/article/2e89d9ed488e4c3fb56e29dec822f87f
Description
Summary:Introduction Mixed-species biofilms are involved in a wide variety of infections. We studied the synergistic interactions during dual-species biofilm formation among isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia. Methods Isolates were cultured as single-species and all possible combinations of dual-species biofilms. Results The 61 A. baumannii biofilms increased by 26-fold when cultured with S. maltophilia isolates; 62 A. baumannii biofilms increased by 20-fold when cultured with S. maltophilia isolates; and 31 P. aeruginosa biofilms increased by 102-fold when cultured with S. maltophilia 106. Conclusions Synergy was observed between two isolates, including those that inherently lacked biofilm formation ability.

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