Plausible reasons for the resurgence of Mpox (formerly Monkeypox): an overview

Abstract Poxviruses are large and diversified viruses that cause an emerging zoonotic disease known as monkeypox (mpox). In the past, mpox predominated primarily in the rural rainforests of Central and West Africa. Recently, the exportation of mpoxv from Africa to other continents has been progressi...

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Bibliographic Details
Published in:Tropical Diseases, Travel Medicine and Vaccines
Main Authors: Arghavan Zebardast, Tayebeh Latifi, Nazanin-Zahra Shafiei-Jandaghi, Mehdi Gholami Barzoki, Somayeh Shatizadeh Malekshahi
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2023
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Online Access:https://doi.org/10.1186/s40794-023-00209-6
https://doaj.org/article/2518dea1784c49b9abb009f08ebcc73d
Description
Summary:Abstract Poxviruses are large and diversified viruses that cause an emerging zoonotic disease known as monkeypox (mpox). In the past, mpox predominated primarily in the rural rainforests of Central and West Africa. Recently, the exportation of mpoxv from Africa to other continents has been progressively reported. However, the lack of travel history to Africa in most of the currently reported cases in 2022 promotes the sign of changing epidemiology of this disease. Concerns over the geographic distribution and continued resurgence of mpox is growing. In this review, we addressed the geographic distribution, transmission, reasons for the resurgence of mpox, and vaccination. Although the precise cause of the resurgence in mpox cases is mostly unknown, several suggested factors are believed to be waning immunity, accumulation of unvaccinated people, ecological conditions, risk behaviors of men who have sex with men, and genetic evolution.