Mechanisms of medicinal plants in the treatment of diabetic wound

Wound repair is noticeably prolonged in a diabetic state due to a faulty inflammatory process and an underlying neuropathy. Several medicinal plants and their products have been of prime importance for the management of wounds over the years. Various mechanisms whereby medicinal plants elicit their...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Oluwakemi V Adeleke, Stephen A Adefegha, Ganiyu Oboh
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2023
Subjects:
Online Access:https://doi.org/10.4103/2221-1691.378597
https://doaj.org/article/1f42af3c66254c348b197b609fe21393
Description
Summary:Wound repair is noticeably prolonged in a diabetic state due to a faulty inflammatory process and an underlying neuropathy. Several medicinal plants and their products have been of prime importance for the management of wounds over the years. Various mechanisms whereby medicinal plants elicit their action in wound repair are revealed and some plants are proven to be experimentally effective in enhancing wound closure and achieving healing. The mechanisms identified include hyperglycemic control, alleviation of physiological inflammation, controlled oxidative stress, infection control, and influence on gene expression. Information in this review was sourced from research and review articles in electronic databases such as Web of Science, Scopus, PubMed, and Google Scholar.