Pharmacological and analytical aspects of artemisinin for malaria: Advances and challenges

Malaria remains a major tropical health burden owing to the development of resistance and decreased sensitivity to the frequently used conventional antimalarial drugs. The drug like artemisinin possesses potent antimalarial activities, but has some limitations. Therefore, new strategies are to be im...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Medicine
Main Authors: Sravani Karri, Sanjay Sharma, Ginpreet Kaur
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2019
Subjects:
Online Access:https://doi.org/10.4103/1995-7645.262562
https://doaj.org/article/16b24a379e55418b80c1a6db51729431
Description
Summary:Malaria remains a major tropical health burden owing to the development of resistance and decreased sensitivity to the frequently used conventional antimalarial drugs. The drug like artemisinin possesses potent antimalarial activities, but has some limitations. Therefore, new strategies are to be implemented for optimal utilization of artemisinin to improve its therapeutic effectiveness and to overcome its limitations. The present review focuses on present scenario of malaria and pharmacological as well as analytical aspects of artemisinin. Data from 2000 to 2018 were collected from NCBI for understanding the various analytical techniques used for estimation of artemisinin. This review will reveal the facts about artemisinin which can be utilized to develop novel drug delivery system either in a combination or as alone for the wellbeing of the patients suffering from malaria.