Acute gouty arthritis as a manifestation of immune reconstitution inflammatory syndrome after initiation of antiretroviral therapy

Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected subjects initiating antiretroviral therapy most commonly involves new or worsening manifestations of previously subclinical or overt infectious diseases. Reports of non-infectious IRIS are much less common but represent important dia...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Walter de Araujo Eyer-Silva, Maria Cecília da Fonseca Salgado, Jorge Francisco da Cunha Pinto, Fernando Raphael de Almeida Ferry, Rogério Neves-Motta, Marcelo Costa Velho Mendes de Azevedo, Carlos Alberto Morais-de-Sá
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2012
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Online Access:https://doi.org/10.1590/S0036-46652012000400009
https://doaj.org/article/166565224022496e86bd64d12792f4e5
Description
Summary:Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected subjects initiating antiretroviral therapy most commonly involves new or worsening manifestations of previously subclinical or overt infectious diseases. Reports of non-infectious IRIS are much less common but represent important diagnostic and treatment challenges. We report on a 34-year-old HIV-infected male patient with no history of gout who developed acute gouty arthritis in a single joint one month after initiating highly active antiretroviral therapy.