Immune response in Rattus rattus norvegicus rats against infection with giardiasis by the lipopolysaccharide extracted from Escherichia coli II. Blood picture

The study investigated, for the first time, the effect of the lipopolysaccharide (LPS) secreted by Escherichia coli, as an immunomodulator, against infection with giardiasis caused by Giardia lamblia in Rattus rattus norvegicus. The pathological changes occurred in the rats treated with LPS, were fo...

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Bibliographic Details
Published in:Iraqi Journal of Veterinary Sciences
Main Authors: S. Y. Yousif, A. A. Ali
Format: Article in Journal/Newspaper
Language:Arabic
English
Published: University of Mosul, College of Veterinary Medicine 2007
Subjects:
Online Access:https://doi.org/10.33899/ijvs.2007.5617
https://doaj.org/article/14cbd67855194ec09eb04e828331b447
Description
Summary:The study investigated, for the first time, the effect of the lipopolysaccharide (LPS) secreted by Escherichia coli, as an immunomodulator, against infection with giardiasis caused by Giardia lamblia in Rattus rattus norvegicus. The pathological changes occurred in the rats treated with LPS, were followed in comparison with the control groups, along the experiments period, depending on many criteria, included the changes in total and differentiated count of leukocytes. The results showed an elevation in the total count of leukocytes, expressed by elevation in neutrophils, variation in monocytes numbers accompanied with a decrease in lymphocytes numbers in treated rats in comparisons with the control groups. Results are provided that (LPS) modulates the immune defence of rats against infection with giardiasis.