Susceptibilidad de Neisseria gonorrhoeae a los antibioticos B-lactamicos, tetraciclinas y quinolonas

• Main Authors: Sandoval Marisol, Guevara Armando, Ward Lumar, Regina Ramos, Suarez Yuraima, Salomon Marlly
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2007
• Subjects: Resistencia; gonorrea; Neisseria gonorrhoeae; Resistance; gonorrhoea; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic
• Online Access: https://doaj.org/article/145037014fff4eaf98cc0ae78b2b8751

Abstract: Neisseria gonorrhoeae susceptibility to B-lactamics antibiotic, tetraciclines, and quinolones was studied in strains isolated from patients with gonococcic cervicitis and/or urethritis that were to consultation of Infections of Sexual Transmission of The Ambulatory Urban type II, in a neighborhood of Ciudad Bolívar from July to August - 2003. The samples were seeded in Agar Blood, GC Agar Base and 1% defined growth supplement, Agar Thayer Martin; making simultaneously a Gram stain. Suspicious colonies were identified by means of oxidase test and sugar degradation in CTA medium. The production of -lactamases was investigated of by means of the acidimetric method. Susceptibility tests were made in GC Agar Base and 1% defined growth supplement. Penicilline, ceftriaxone, tetracicline, and Ciprofloxacin were used. 50 strains were isolated of Neisseria gonorrhoeae that represented 43.85% of patients with gonococci infections (Urethritis and/or cervicitis) of which 82% belonged to masculine sex. There was no evidence of production of ß-lactamases in the studied strains. As far as the susceptibility to the antimicrobial drugs it was found 46% strains resistant to penicillin, 42% to tetraciclines. Ceftriaxone and ciprofloxacin showed a good activity against N. gonorrhoeae with 98 and 92% of sensitivity, respectively. Resumen: Se estudió la susceptibilidad de Neisseria gonorrhoeae a los antibióticos B-lactámicos, tetraciclinas y quinolonas, en cepas aisladas de pacientes con cervicitis y/o uretritis gonocóccicas que asitieron a la consulta de Infecciones de Transmisión Sexual del Ambulatorio Urbano tipo II, El Perú en Ciudad Bolívar, Julio-Agosto del 2003. Las muestras fueron inoculadas en Agar Sangre, Agar Base GC con suplemento nutricional al 1% y Agar Thayer Martin; realizando simultáneamente coloración de Gram. Las colonias sospechosas fueron identificadas mediante el test de oxidasa, y la degradación de azúcares en medio CTA. Se investigó la producción de -lactamasa mediante el método acidimétrico. Las ...