The role of extracellular vesicles in malaria biology and pathogenesis

• Published in: Malaria Journal
• Main Authors: Natalia Guimaraes Sampaio, Lesley Cheng, Emily M. Eriksson
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2017
• Subjects: Extracellular vesicles; Exosomes; Microparticles; Microvesicle; Pathogenesis; Plasmodium; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1186/s12936-017-1891-z; https://doaj.org/article/13e242bc0197457fb77b3c39f8b72f81

Abstract In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed important roles for extracellular vesicles in disease pathogenesis and susceptibility, as well as cell–cell communication and immune responses. Here, work relating to extracellular vesicles in malaria is reviewed, and the areas that remain unknown and require further investigations are highlighted.