The role of extracellular vesicles in malaria biology and pathogenesis

Abstract In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed important roles for extracellular vesicles in disease pathogenesis and susceptibility...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Natalia Guimaraes Sampaio, Lesley Cheng, Emily M. Eriksson
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2017
Subjects:
Extracellular vesicles
Exosomes
Microparticles
Microvesicle
Pathogenesis
Plasmodium
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1186/s12936-017-1891-z
https://doaj.org/article/13e242bc0197457fb77b3c39f8b72f81
Description
Summary:Abstract In the past decade, research on the functions of extracellular vesicles in malaria has expanded dramatically. Investigations into the various vesicle types, from both host and parasite origin, has revealed important roles for extracellular vesicles in disease pathogenesis and susceptibility, as well as cell–cell communication and immune responses. Here, work relating to extracellular vesicles in malaria is reviewed, and the areas that remain unknown and require further investigations are highlighted.

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