A schistosomiasis research agenda.

There is a long and rich history of research and control in the field of schistosomiasis that has resulted in major scientific and public health accomplishments. Examples of such findings and accomplishments include immunologic regulation in chronic infections, the association of helminth infections...

Full description

Bibliographic Details
Published in:PLoS Neglected Tropical Diseases
Main Authors: Daniel G Colley, W Evan Secor
Format: Article in Journal/Newspaper
Language:English
Published: Public Library of Science (PLoS) 2007
Subjects:
Online Access:https://doi.org/10.1371/journal.pntd.0000032
https://doaj.org/article/13d03af4a29b4f1aa73e52ba047576ed
Description
Summary:There is a long and rich history of research and control in the field of schistosomiasis that has resulted in major scientific and public health accomplishments. Examples of such findings and accomplishments include immunologic regulation in chronic infections, the association of helminth infections with Th1-regulating Th2-type immune responses, the critical role of interleukin-13 in fibrogenesis, and the development and validation of the "dose pole" for determining praziquantel dosages in the field. Perhaps in part because of this broad and successful history, those who work on schistosomiasis come from a wide variety of backgrounds and interests. While such variety is enriching to the field, it sometimes results in diverse opinions about which of the many research opportunities should be pursued. Such diversity, we believe, has at times led to a divisiveness that has harmed overall progress in the field. Partly in response to such events, we have worked with as many of those interested in schistosomiasis as we could identify to develop what we feel is a comprehensive and cohesive agenda for schistosomiasis research.