New sepsis biomarkers

Sepsis remains a leading cause of death in the intensive care units and in all age groups worldwide. Early recognition and diagnosis are key to achieving improved outcomes. Therefore, novel biomarkers that might better inform clinicians treating such patients are surely needed. The main attributes o...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Dolores Limongi, Cartesio D'Agostini, Marco Ciotti
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2016
Subjects:
Online Access:https://doi.org/10.1016/j.apjtb.2016.04.005
https://doaj.org/article/10c0e9f6d27a429eadbd5363ee328384
Description
Summary:Sepsis remains a leading cause of death in the intensive care units and in all age groups worldwide. Early recognition and diagnosis are key to achieving improved outcomes. Therefore, novel biomarkers that might better inform clinicians treating such patients are surely needed. The main attributes of successful biomarkers would be high sensitivity, specificity, possibility of bedside monitoring and financial accessibility. A panel of sepsis biomarkers along with currently used laboratory tests will facilitate earlier diagnosis, timely treatment and improved outcome may be more effective than single biomarkers. In this review, we summarize the most recent advances on sepsis biomarkers evaluated in clinical and experimental studies.