Hepatitis C virus in monozygotic twins

A case of a pregnant patient with chronic hepatitis C who gave birth to monozygotic twins that were infected with HCV is reported. One of the newborns was positive for HCV-RNA in blood sample collected 12 hours after delivery. The other newborn was negative for HCV-RNA at birth, but was detected HCV...

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Bibliographic Details
Main Authors: Fernando L. GONÇALES JR, Raquel S. B. STUCCHI, Maria Helena P. PAVAN, Rodrigo N. ANGERAMI, Neiva S. L. GONÇALES
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2000
Subjects:
HCV Transmission
Monozygotic twins
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doaj.org/article/0a943d581b0740c0a4e3863a09900dfe
Description
Summary:A case of a pregnant patient with chronic hepatitis C who gave birth to monozygotic twins that were infected with HCV is reported. One of the newborns was positive for HCV-RNA in blood sample collected 12 hours after delivery. The other newborn was negative for HCV-RNA at birth, but was detected HCV viremia at three months of age. The results have led to the conclusion that one of the twins was probably contaminated in the intrauterine period, while the other acquired the infection in the perinatal period. Both were negative for HCV-RNA and for anti-HCV in the serum samples collected at nine months of age. The report describes the changes in the laboratory tests conducted in mother and twins until 29 months after delivery.

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