Dengue epidemic in the state of Rio de Janeiro, Brazil: virological and epidemiological aspects Epidemia de dengue no Estado do Rio de Janeiro, Brasil: aspectos virológicos e epidemiológicos

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Marize P. Miagostovich, Rita M.R. Nogueira, Silvia M.B. Cavalcanti, Keyla B.F. Marzochi, Hermann G. Schatzmayr
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1993
• Subjects: DEN-1 Virus isolation; Brazil; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/S0036-46651993000200006; https://doaj.org/article/078682d5319d4389a9a0a7ef773dd984

Laboratorial studies were carried out on 3178 patients with signs and symptoms suggestive of dengue infection from April 1986 to December 1987 in the State of Rio de Janeiro, Brazil. The epidemic had two peaks following the first virus isolation and affected the inhabitants of 17 counties. Both sex and all age groups were affected. Dengue virus type 1 was isolated from 1039 sera and the number of confirmed cases was increased to 1874 (59%) by MAC-ELISA. Isolation rate confirmed cases reached 80% in the specimens obtained until the 4th day after the onset of disease and viraemia ranged from 10 3.0 to 10(8.5) TCID50/ml. Foram realizados estudos laboratoriais em 3178 pacientes com sinais e sintomas sugestivos de infecção por dengue no Estado do Rio de Janeiro, no período de abril de 1986 a dezembro de 1987. A epidemia apresentou 2 picos e afetou residentes de 17 municípios. Ambos os sexos e todos os grupos etários foram igualmente afetados. Dengue virus tipo 1 foi isolado de 1039 soros e a utilização do MAC-ELISA elevou para 1874 (59%) o número de casos confirmados. Nestes casos, a taxa de isolamento alcançou 80% nos espécimens obtidos até o quarto dia após o início da doença. A magnitude da viremia variou de 10(3.0) a 10 8.0 TCDI50/ml.