Intestinal microbiota and HIV-1 infection

The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be altered due to pathological conditions, diet co...

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Bibliographic Details
Published in:Journal of Venomous Animals and Toxins including Tropical Diseases
Main Authors: E. B. S. M. Trindade, L. R. Souza, C. A. M. Lopes, P. C. M. Pereira
Format: Article in Journal/Newspaper
Language:English
Published: SciELO 2007
Subjects:
Online Access:https://doi.org/10.1590/S1678-91992007000200003
https://doaj.org/article/04d6b189b8e140f98d6a753c322687a9
Description
Summary:The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be altered due to pathological conditions, diet composition, gastrointestinal disturbances and/or drug ingestion. The present review aimed at contributing to the discussion about changes in the intestinal microbiota due to HIV-1 infection, focusing on the triad infection-microbiota-nutrition as factors that promote intestinal bacterial imbalance. Intestinal microbiota alterations can be due to the HIV-1 infection as a primary factor or the pharmacotherapy employed, or they can be one of the consequences of the disease.