Vertical transmission of maternal COVID-19 antibodies after CoronaVac vaccine: A case report

Abstract The use of coronavirus disease 2019 RNA vaccines in pregnant women led to reports on the first cases of newborns with antibodies to sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a phenomenon that was unknown when using immunizations with inactivated viruses. Thus, this study...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Bruno Thizon Menegali, Fabiana Schuelter-Trevisol, Alexandre Naime Barbosa, Talita Menegali Izidoro, Otto Henrique May Feurschuette, Chaiana Esmeraldino Mendes Marcon, Daisson José Trevisol
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
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Online Access:https://doi.org/10.1590/0037-8682-0385-2021
https://doaj.org/article/03252038b3aa493b9731b8dcb4ca1ca6
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Summary:Abstract The use of coronavirus disease 2019 RNA vaccines in pregnant women led to reports on the first cases of newborns with antibodies to sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a phenomenon that was unknown when using immunizations with inactivated viruses. Thus, this study aimed to report a case of passive anti-SARS-CoV-2 immunity in a newborn through immunoprophylaxis of a pregnant woman who received the CoronaVac® vaccine in the third trimester of pregnancy. Twenty-four hours after delivery, samples were collected from the newborn and screened by enzyme immunoassays, which revealed antibodies to SARS-CoV-2.