Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst

Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipaseB of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DK...

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Published in:Chemistry – A European Journal
Main Authors: Gustafson, Karl P. J., Görbe, Tamás, deGonzalo‐Calvo, Gonzalo, Yuan, Ning, Schreiber, Cynthia L., Shchukarev, Andrey, Tai, Cheuk‐Wai, Persson, Ingmar, Zou, Xiaodong, Bäckvall, Jan‐E.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley-VCH 2019
Subjects:
info:eu-repo/classification/ddc/540
Antarc*
Antarctica
Online Access:https://bib-pubdb1.desy.de/record/426151
https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22
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spelling ftdesyvdb:oai:bib-pubdb1.desy.de:426151 2023-05-15T13:58:55+02:00 Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst Gustafson, Karl P. J. Görbe, Tamás deGonzalo‐Calvo, Gonzalo Yuan, Ning Schreiber, Cynthia L. Shchukarev, Andrey Tai, Cheuk‐Wai Persson, Ingmar Zou, Xiaodong Bäckvall, Jan‐E. DE 2019 https://bib-pubdb1.desy.de/record/426151 https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22 eng eng Wiley-VCH info:eu-repo/semantics/altIdentifier/pmid/pmid:31050831 info:eu-repo/semantics/altIdentifier/issn/1521-3765 info:eu-repo/semantics/altIdentifier/issn/0947-6539 info:eu-repo/semantics/altIdentifier/doi/10.1002/chem.201901418 info:eu-repo/semantics/altIdentifier/wos/WOS:000475680200007 https://bib-pubdb1.desy.de/record/426151 https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22 info:eu-repo/semantics/closedAccess Chemistry - a European journal 25(39), 9174 - 9179 (2019). doi:10.1002/chem.201901418 info:eu-repo/classification/ddc/540 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2019 ftdesyvdb https://doi.org/10.1002/chem.201901418 2022-06-30T20:20:13Z Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipaseB of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DKR and the recyclability of the catalysts was studied. Extensive efforts to further elucidate the structure of the catalyst are presented. Article in Journal/Newspaper Antarc* Antarctica DESY Publication Database (PUBDB) Chemistry – A European Journal 25 39 9174 9179
institution Open Polar
collection DESY Publication Database (PUBDB)
op_collection_id ftdesyvdb
language English
topic info:eu-repo/classification/ddc/540
spellingShingle info:eu-repo/classification/ddc/540
Gustafson, Karl P. J.
Görbe, Tamás
deGonzalo‐Calvo, Gonzalo
Yuan, Ning
Schreiber, Cynthia L.
Shchukarev, Andrey
Tai, Cheuk‐Wai
Persson, Ingmar
Zou, Xiaodong
Bäckvall, Jan‐E.
Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
topic_facet info:eu-repo/classification/ddc/540
description Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipaseB of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DKR and the recyclability of the catalysts was studied. Extensive efforts to further elucidate the structure of the catalyst are presented.
format Article in Journal/Newspaper
author Gustafson, Karl P. J.
Görbe, Tamás
deGonzalo‐Calvo, Gonzalo
Yuan, Ning
Schreiber, Cynthia L.
Shchukarev, Andrey
Tai, Cheuk‐Wai
Persson, Ingmar
Zou, Xiaodong
Bäckvall, Jan‐E.
author_facet Gustafson, Karl P. J.
Görbe, Tamás
deGonzalo‐Calvo, Gonzalo
Yuan, Ning
Schreiber, Cynthia L.
Shchukarev, Andrey
Tai, Cheuk‐Wai
Persson, Ingmar
Zou, Xiaodong
Bäckvall, Jan‐E.
author_sort Gustafson, Karl P. J.
title Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
title_short Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
title_full Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
title_fullStr Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
title_full_unstemmed Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
title_sort chemoenzymatic dynamic kinetic resolution of primary benzylic amines using $pd^{0}‐calb$ clea as a biohybrid catalyst
publisher Wiley-VCH
publishDate 2019
url https://bib-pubdb1.desy.de/record/426151
https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22
op_coverage DE
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_source Chemistry - a European journal 25(39), 9174 - 9179 (2019). doi:10.1002/chem.201901418
op_relation info:eu-repo/semantics/altIdentifier/pmid/pmid:31050831
info:eu-repo/semantics/altIdentifier/issn/1521-3765
info:eu-repo/semantics/altIdentifier/issn/0947-6539
info:eu-repo/semantics/altIdentifier/doi/10.1002/chem.201901418
info:eu-repo/semantics/altIdentifier/wos/WOS:000475680200007
https://bib-pubdb1.desy.de/record/426151
https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22
op_rights info:eu-repo/semantics/closedAccess
op_doi https://doi.org/10.1002/chem.201901418
container_title Chemistry – A European Journal
container_volume 25
container_issue 39
container_start_page 9174
op_container_end_page 9179
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