Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using $Pd^{0}‐CalB$ CLEA as a Biohybrid Catalyst
Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipaseB of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DK...
Published in: | Chemistry – A European Journal |
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Main Authors: | , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley-VCH
2019
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Subjects: | |
Online Access: | https://bib-pubdb1.desy.de/record/426151 https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2019-03624%22 |
Summary: | Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme aggregates of lipaseB of Candida antarctica (CalB CLEA) for the dynamic kinetic resolution (DKR) of benzylic amines. A set of amines were demonstrated to undergo an efficient DKR and the recyclability of the catalysts was studied. Extensive efforts to further elucidate the structure of the catalyst are presented. |
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