Patterns of homozygosity in insular and continental goat breeds.

BACKGROUND Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds...

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Bibliographic Details
Main Authors: Cardoso, Taina F, Amills, Marcel, Bertolini, Francesca, Rothschild, Max, Marras, Gabriele, Boink, Geert, Jordana, Jordi, Capote, Juan, Carolan, Sean, Hallsson, Jón H, Kantanen, Juha, Pons, Agueda, Lenstra, Johannes A, AdaptMap, Consortium
Format: Text
Language:English
Published: BioMed Central 2018
Subjects:
590 Animals Zoology
630 Agriculture
Iceland
Online Access:https://dx.doi.org/10.7892/boris.127323
https://boris.unibe.ch/127323/
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Summary:BACKGROUND Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. RESULTS Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and F values (P value

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