Chromosome-level genome provides insight into the evolution and conservation of the threatened goral (Naemorhedus goral) ...

Abstract Background Gorals Naemorhedus resemble both goats and antelopes, which prompts much debate about the intragenus species delimitation and phylogenetic status of the genus Naemorhedus within the subfamily Caprinae. Their evolution is believed to be linked to the uplift of the Qinghai-Tibet Pl...

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Bibliographic Details
Main Authors: Sun, Nan, Ma, Xiao-Ying, Shi, Guang-Hong, Yang, Xiao-Hong, Li, Wei, Feng, Chen-Guang, Mi, Da, Li, Guo-Gang, Lu, Ji-Qi
Format: Article in Journal/Newspaper
Language:unknown
Published: figshare 2024
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Online Access:https://dx.doi.org/10.6084/m9.figshare.c.7038224
https://springernature.figshare.com/collections/Chromosome-level_genome_provides_insight_into_the_evolution_and_conservation_of_the_threatened_goral_Naemorhedus_goral_/7038224
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Summary:Abstract Background Gorals Naemorhedus resemble both goats and antelopes, which prompts much debate about the intragenus species delimitation and phylogenetic status of the genus Naemorhedus within the subfamily Caprinae. Their evolution is believed to be linked to the uplift of the Qinghai-Tibet Plateau (QTP). To better understand its phylogenetics, the genetic information is worth being resolved. Results Based on a sample from the eastern margin of QTP, we constructed the first reference genome for Himalayan goral Naemorhedus goral, using PacBio long-read sequencing and Hi-C technology. The 2.59 Gb assembled genome had a contig N50 of 3.70 Mb and scaffold N50 of 106.66 Mb, which anchored onto 28 pseudo chromosomes. A total of 20,145 protein-coding genes were predicted in the assembled genome, of which 99.93% were functionally annotated. Phylogenetically, the goral was closely related to muskox on the mitochondrial genome level and nested into the takin-muskox clade on the genome tree, rather than other ...