Detection and molecular analysis of Pseudorabies virus from free-ranging Italian wolves (Canis lupus italicus) in Italy - a case report ...

Abstract Background The only natural hosts of Pseudorabies virus (PRV) are members of the family Suidae (Sus scrofa scrofa). In mammals, the infection is usually fatal and typically causes serious neurologic disease. This study describes four Aujeszky’s disease cases in free-ranging Italian wolves (...

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Bibliographic Details
Main Authors: Moreno, Ana, Musto, Carmela, Gobbi, Marco, Maioli, Giulia, Menchetti, Marika, Trogu, Tiziana, Paniccià, Marta, Lavazza, Antonio, Delogu, Mauro
Format: Article in Journal/Newspaper
Language:unknown
Published: figshare 2024
Subjects:
Online Access:https://dx.doi.org/10.6084/m9.figshare.c.7007336.v1
https://springernature.figshare.com/collections/Detection_and_molecular_analysis_of_Pseudorabies_virus_from_free-ranging_Italian_wolves_Canis_lupus_italicus_in_Italy_-_a_case_report/7007336/1
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Summary:Abstract Background The only natural hosts of Pseudorabies virus (PRV) are members of the family Suidae (Sus scrofa scrofa). In mammals, the infection is usually fatal and typically causes serious neurologic disease. This study describes four Aujeszky’s disease cases in free-ranging Italian wolves (Canis lupus italicus). In Italy, the wolf is a strictly protected species and is in demographic expansion. Case presentation Three wolves (Wolf A, B, and C) were found in a regional park in Northern Italy, and one (Wolf D) was found in Central Italy. Wolf A and D were alive at the time of the finding and exhibited a fatal infection with epileptic seizures and dyspnoea, dying after a few hours. Wolf B presented scratching lesions under the chin and a detachment of the right earlobe, whilst Wolf C was partially eaten. The wolves showed hepatic congestion, diffuse enteritis, moderate pericardial effusion, severe bilateral pneumonia, and diffuse hyperaemia in the brain. The diagnostic examinations included virological ...