The transcriptomic responses of Atlantic salmon (Salmo salar) to high temperature stress alone, and in combination with moderate hypoxia

Abstract Background Increases in ocean temperatures and in the frequency and severity of hypoxic events are expected with climate change, and may become a challenge for cultured Atlantic salmon and negatively affect their growth, immunology and welfare. Thus, we examined how an incremental temperatu...

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Bibliographic Details
Main Authors: Beemelmanns, Anne, Zanuzzo, Fábio S., Xue, Xi, Rebeccah M. Sandrelli, Rise, Matthew L., A. Kurt Gamperl
Format: Article in Journal/Newspaper
Language:unknown
Published: figshare 2021
Subjects:
Online Access:https://dx.doi.org/10.6084/m9.figshare.c.5373431
https://springernature.figshare.com/collections/The_transcriptomic_responses_of_Atlantic_salmon_Salmo_salar_to_high_temperature_stress_alone_and_in_combination_with_moderate_hypoxia/5373431
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Summary:Abstract Background Increases in ocean temperatures and in the frequency and severity of hypoxic events are expected with climate change, and may become a challenge for cultured Atlantic salmon and negatively affect their growth, immunology and welfare. Thus, we examined how an incremental temperature increase alone (Warm & Normoxic-WN: 12 → 20 °C; 1 °C week− 1), and in combination with moderate hypoxia (Warm & Hypoxic-WH: ~ 70% air saturation), impacted the salmon’s hepatic transcriptome expr\ession compared to control fish (CT: 12 °C, normoxic) using 44 K microarrays and qPCR. Results Overall, we identified 2894 differentially expressed probes (DEPs, FDR