Early life swimming pool exposure and asthma onset in children – a case-control study ...

Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with...

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Bibliographic Details
Main Authors: Andersson, Martin, Backman, Helena, Nordberg, Gunnar, Hagenbjörk, Annika, Hedman, Linnea, Eriksson, Kåre, Forsberg, Bertil, Rönmark, Eva
Format: Article in Journal/Newspaper
Language:unknown
Published: figshare 2018
Subjects:
Online Access:https://dx.doi.org/10.6084/m9.figshare.c.4067153
https://springernature.figshare.com/collections/Early_life_swimming_pool_exposure_and_asthma_onset_in_children_a_case-control_study/4067153
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Summary:Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16–17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews. Trichloramine concentrations in the pool buildings were measured. Skin prick test results for inhalant allergens were available from previous examinations of the cohort. The risk for asthma was analyzed in relation to the cumulative trichloramine exposure before onset of asthma. Results The participation rate was high in the original cohort (88 to 96%), and in the case-control study (80%). Trichloramine concentrations ranged from 0.020 to 0.55 mg/m3 (mean ...