Erratum: Epidemiologic Study of Charcot-Marie-Tooth Disease: A Systematic Review

• Main Authors: Barreto L.C.L.S., Oliveira, F.S., Nunes, P.S., I.M.P., De França Costa, Garcez, C.A., Goes, G.M., Neves E.L.A., De Souza Siqueira Quintans, J., De Souza Araújo, A.A.
• Format: Dataset
• Language: unknown
• Published: Karger Publishers 2017
• Subjects: Medicine; Charcot; Norway; Iceland
• Online Access: https://dx.doi.org/10.6084/m9.figshare.5241928; https://karger.figshare.com/articles/dataset/Erratum_Epidemiologic_Study_of_Charcot-Marie-Tooth_Disease_A_Systematic_Review/5241928

Background: Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy. CMT is classified into 2 main subgroups: CMT type 1 (CMT1; demyelinating form) and CMT type 2 (CMT2; axonal form). The objectives of this study were to systematically review and assess the quality of studies reporting the incidence and/or prevalence of CMT worldwide. Summary: A total of 802 studies were initially identified, with only 12 meeting the inclusion criteria. CMT prevalence was reported in 10 studies and ranged from 9.7/100,000 in Serbia to 82.3/100,000 in Norway. The frequency of the main subtypes varied from 37.6 to 84% for CMT1 and from 12 to 35.9% for CMT2; the country with the lowest prevalence of CMT1 was Norway, and the country with the highest prevalence of CMT1 was Iceland; on the other hand, CMT2 was least prevalent in the United Kingdom and most prevalent in Norway. Key Messages: This review reveals the gaps that still exist in the epidemiological knowledge of CMT around the world. Published studies are of varying quality and utilise different methodologies, thus precluding a robust conclusion. Additional research focusing on epidemiological features of CMT in different nations and different ethnic groups is needed.