A new sesquiterpene lactone from fungus Eutypella sp. D-1 ...

• Main Authors: Zhou, Yue, Zhang, Yi-Xin, Zhang, Jian-Peng, Yu, Hao-Bing, Liu, Xiao-Yu, Lu, Xiao-Ling, Jiao, Bing-Hua
• Format: Text
• Language: unknown
• Published: Taylor & Francis 2017
• Subjects: Biochemistry; Microbiology; FOS Biological sciences; Biotechnology; Environmental Sciences not elsewhere classified; Chemical Sciences not elsewhere classified; Ecology; Biological Sciences not elsewhere classified; Arctic
• Online Access: https://dx.doi.org/10.6084/m9.figshare.4738309; https://tandf.figshare.com/articles/journal_contribution/A_new_sesquiterpene_lactone_from_fungus_i_Eutypella_i_sp_D-1/4738309

We isolated and identified a new sesquiterpene lactone which we named eut -Guaiane sesquiterpene ( 1 ), along with four cytochalasins from the fungus Eutypella sp. derived from the soil of high latitude of Arctic. The new structure was determined by spectroscopic studies such as 1D and 2D NMR and MS analyses, while the known compounds were identified by comparison of the NMR data with those in literatures. New compound 1 exhibited strong antibacterial activity against Escherichia coli , Bacillus subtilis and Staphylococcus aureus . Besides, it showed a little cytotoxicity against SGC7901 cell line. ...