A new sesquiterpene lactone from fungus Eutypella sp. D-1 ...

We isolated and identified a new sesquiterpene lactone which we named eut -Guaiane sesquiterpene ( 1 ), along with four cytochalasins from the fungus Eutypella sp. derived from the soil of high latitude of Arctic. The new structure was determined by spectroscopic studies such as 1D and 2D NMR and MS...

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Bibliographic Details
Main Authors: Zhou, Yue, Zhang, Yi-Xin, Zhang, Jian-Peng, Yu, Hao-Bing, Liu, Xiao-Yu, Lu, Xiao-Ling, Jiao, Bing-Hua
Format: Text
Language:unknown
Published: Taylor & Francis 2017
Subjects:
Biochemistry
Microbiology
FOS Biological sciences
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Ecology
Biological Sciences not elsewhere classified
Arctic
Online Access:https://dx.doi.org/10.6084/m9.figshare.4738309
https://tandf.figshare.com/articles/journal_contribution/A_new_sesquiterpene_lactone_from_fungus_i_Eutypella_i_sp_D-1/4738309
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Summary:We isolated and identified a new sesquiterpene lactone which we named eut -Guaiane sesquiterpene ( 1 ), along with four cytochalasins from the fungus Eutypella sp. derived from the soil of high latitude of Arctic. The new structure was determined by spectroscopic studies such as 1D and 2D NMR and MS analyses, while the known compounds were identified by comparison of the NMR data with those in literatures. New compound 1 exhibited strong antibacterial activity against Escherichia coli , Bacillus subtilis and Staphylococcus aureus . Besides, it showed a little cytotoxicity against SGC7901 cell line. ...

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