Characteristics of women with ischemic sudden cardiac death ...

• Main Authors: Hookana, I., Holmström, L., Eskuri, M. A. E., Pakanen, L., Ollila, M. M., Kiviniemi, A. M., Kenttä, T., Vähätalo, J., Tulppo, M., Lepojärvi, E. S., Piltonen, T., Perkiömäki, J., Tikkanen, J. T., Huikuri, H. V., Junttila, M. J.
• Format: Text
• Language: unknown
• Published: Taylor & Francis 2023
• Subjects: Medicine; Cell Biology; Genetics; FOS Biological sciences; Neuroscience; Pharmacology; Biotechnology; Immunology; FOS Clinical medicine; Mathematical Sciences not elsewhere classified; Developmental Biology; Cancer; Computational Biology; Northern Finland
• Online Access: https://dx.doi.org/10.6084/m9.figshare.24249658; https://tandf.figshare.com/articles/journal_contribution/Characteristics_of_women_with_ischemic_sudden_cardiac_death/24249658

Sudden cardiac death (SCD) is a significant mode of death causing 15-20% of all deaths in high-income countries. Coronary artery disease (CAD) is the most common cause of SCD in both sexes, and SCD is often the first manifestation of underlying CAD in women. This case-control study aimed to determine the factors associated with SCD due to CAD in women. The study group consisted of women with CAD-related SCD ( N = 888) derived from the Fingesture study conducted in Northern Finland from 1998 to 2017. All SCDs underwent medicolegal autopsy. The control group consisted of women with angiographically verified CAD without SCD occurring during the 5-year-follow-up ( N = 610). To compare these groups, we used medical records, autopsy findings, echocardiograms, and electrocardiograms (ECGs). Subjects with SCD were older (73.2 ± 11.3 vs. 68.8 ± 8.0, p < 0.001) and were more likely to be smokers or ex-smokers (37.1% vs. 27.6%, p = 0.045) compared to control patients. The proportion of subjects with prior myocardial ...