Characteristics of women with ischemic sudden cardiac death ...

Sudden cardiac death (SCD) is a significant mode of death causing 15-20% of all deaths in high-income countries. Coronary artery disease (CAD) is the most common cause of SCD in both sexes, and SCD is often the first manifestation of underlying CAD in women. This case-control study aimed to determin...

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Bibliographic Details
Main Authors: Hookana, I., Holmström, L., Eskuri, M. A. E., Pakanen, L., Ollila, M. M., Kiviniemi, A. M., Kenttä, T., Vähätalo, J., Tulppo, M., Lepojärvi, E. S., Piltonen, T., Perkiömäki, J., Tikkanen, J. T., Huikuri, H. V., Junttila, M. J.
Format: Text
Language:unknown
Published: Taylor & Francis 2023
Subjects:
Medicine
Cell Biology
Genetics
FOS Biological sciences
Neuroscience
Pharmacology
Biotechnology
Immunology
FOS Clinical medicine
Mathematical Sciences not elsewhere classified
Developmental Biology
Cancer
Computational Biology
Northern Finland
Online Access:https://dx.doi.org/10.6084/m9.figshare.24249658
https://tandf.figshare.com/articles/journal_contribution/Characteristics_of_women_with_ischemic_sudden_cardiac_death/24249658
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Summary:Sudden cardiac death (SCD) is a significant mode of death causing 15-20% of all deaths in high-income countries. Coronary artery disease (CAD) is the most common cause of SCD in both sexes, and SCD is often the first manifestation of underlying CAD in women. This case-control study aimed to determine the factors associated with SCD due to CAD in women. The study group consisted of women with CAD-related SCD ( N = 888) derived from the Fingesture study conducted in Northern Finland from 1998 to 2017. All SCDs underwent medicolegal autopsy. The control group consisted of women with angiographically verified CAD without SCD occurring during the 5-year-follow-up ( N = 610). To compare these groups, we used medical records, autopsy findings, echocardiograms, and electrocardiograms (ECGs). Subjects with SCD were older (73.2 ± 11.3 vs. 68.8 ± 8.0, p < 0.001) and were more likely to be smokers or ex-smokers (37.1% vs. 27.6%, p = 0.045) compared to control patients. The proportion of subjects with prior myocardial ...

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