Maternal characteristics and pregnancy outcomes in the NICE birth cohort: an assessment of self-selection bias ...

• Main Authors: Ögge, Linda Englund, Murray, Fiona, Modzelewska, Dominika, Lundqvist, Robert, Nilsson, Staffan, Carré, Helena, Kippler, Maria, Wold, Agnes E., Sandberg, Ann-Sofie, Sandin, Anna, Jacobsson, Bo, Barman, Malin
• Format: Text
• Language: unknown
• Published: Taylor & Francis 2022
• Subjects: Medicine; Cell Biology; Biotechnology; Sociology; FOS Sociology; Biological Sciences not elsewhere classified; Cancer; Northern Sweden; Norrbotten
• Online Access: https://dx.doi.org/10.6084/m9.figshare.17786198; https://tandf.figshare.com/articles/journal_contribution/Maternal_characteristics_and_pregnancy_outcomes_in_the_NICE_birth_cohort_an_assessment_of_self-selection_bias/17786198

Prospective birth cohorts are essential for identifying associations between exposures and outcomes. However, voluntary participation introduces a potential bias due to self selection since the persons that chose to participate may differ in background characteristics and behaviors. To investigate potential bias due to self-selection in the N utritional impact on I mmunological maturation during C hildhood in relation to the E nvironment (NICE) birth cohort in northern Sweden. Women in the NICE birth cohort ( N = 621) were compared to nonparticipating pregnant women in Norrbotten County in northern Sweden who were eligible for participation ( N = 4976) regarding maternal characteristics and lifestyle. Maternal characteristics and pregnancy outcomes were compared between the groups and associations between exposures (smoking, folic acid, BMI, parity, education) and pregnancy outcomes (birth weight and gestational age) were analyzed by linear regression analyses, examining any interaction with the group. NICE ...