Additional file 5 of Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon

• Main Authors: Khan, Yousuf, Jungreis, Irwin, Wright, James, Mudge, Jonathan, Choudhary, Jyoti, Firth, Andrew, Kellis, Manolis
• Format: Text
• Language: unknown
• Published: figshare 2020
• Subjects: Biochemistry; Cell Biology; Genetics; FOS Biological sciences; Molecular Biology; Evolutionary Biology; 69999 Biological Sciences not elsewhere classified; 80699 Information Systems not elsewhere classified; FOS Computer and information sciences; Developmental Biology; 110309 Infectious Diseases; FOS Health sciences; Computational Biology; Orca; Orcinus orca
• Online Access: https://dx.doi.org/10.6084/m9.figshare.11945358.v1; https://springernature.figshare.com/articles/Additional_file_5_of_Evidence_for_a_novel_overlapping_coding_sequence_in_POLG_initiated_at_a_CUG_start_codon/11945358/1

Additional file 5 : Figure S5: Potential functional regions of the ORF-Y protein. a. Predicted ORF-Y protein sequences from representatives (Homo sapiens, Mus musculus, Orcinus orca, and Myotis lucifugus) of different mammalian orders were submitted to the TMHMM server for transmembrane domain prediction. Each vertical red bar represents the likelihood of a position being contained within a transmembrane domain; the blue line indicates whether the portion of the protein is predicted to be intracellular; and the purple line indicates whether the portion of the protein is predicted to be extracellular. The color of the horizontal line near the top of each plot indicates, for each position, whether it is most likely to be intracellular, transmembrane, or extracellular. b. Possible motifs predicted by the ELM database for the portion of the ORF-Y protein that is most conserved.