Phagocyte activity reflects mammalian homeo- and hetero-thermic physiological states ...
(Uploaded by Plazi for the Bat Literature Project) BACKGROUND: Emergence of both viral zoonoses from bats and diseases that threaten bat populations has highlighted the necessity for greater insights into the functioning of the bat immune system. Particularly when considering hibernating temperate b...
Main Authors: | , , , , , , , , |
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Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
Zenodo
2020
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Subjects: | |
Online Access: | https://dx.doi.org/10.5281/zenodo.13533860 https://zenodo.org/doi/10.5281/zenodo.13533860 |
Summary: | (Uploaded by Plazi for the Bat Literature Project) BACKGROUND: Emergence of both viral zoonoses from bats and diseases that threaten bat populations has highlighted the necessity for greater insights into the functioning of the bat immune system. Particularly when considering hibernating temperate bat species, it is important to understand the seasonal dynamics associated with immune response. Body temperature is one of the factors that modulates immune functions and defence mechanisms against pathogenic agents in vertebrates. To better understand innate immunity mediated by phagocytes in bats, we measured respiratory burst and haematology and blood chemistry parameters in heterothermic greater mouse-eared bats (Myotis myotis) and noctules (Nyctalus noctula) and homeothermic laboratory mice (Mus musculus). RESULTS: Bats displayed similar electrolyte levels and time-related parameters of phagocyte activity, but differed in blood profile parameters related to metabolism and red blood cell count. Greater ... |
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