Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France ...
(Uploaded by Plazi for the Bat Literature Project) Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by wholegenome sequencing and compared...
| Main Authors: | , , , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | unknown |
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Zenodo
2013
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| Subjects: | |
| Online Access: | https://dx.doi.org/10.5281/zenodo.13435948 https://zenodo.org/doi/10.5281/zenodo.13435948 |
| Summary: | (Uploaded by Plazi for the Bat Literature Project) Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by wholegenome sequencing and compared to that of the first BBLV strain isolated in 2010 in Germany and with those of all currently identified lyssaviruses. The French isolate [KC169985] showed 98.7 % nucleotide sequence identity to the German BBLV strain [JF311903]. Several organs of the infected French bat were examined by classical rabies diagnostic methods: fluorescent antibody test, cell culture inoculation test and RT-qPCR. Antigen, infectious virus and high viral RNA levels were found in both the brain and salivary glands. Traces of genomic RNA were detected in the bladder, kidney and lung tissue. The results of an investigation of the distribution of lyssaviruses with the detection of infectious virus in the salivary glands suggest a possible mode ... |
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