Genome-wide methylation in the panmictic European eel (Anguilla anguilla) ...

• Main Authors: Liu, Shenglin, Tengstedt, Aja Noersgaard Buur, Jacobsen, Magnus W., Pujolar, Jose Martin, Jónsson, Bjarni, Lobón-Cervià, Javier, Bernatchez, Louis, Hansen, Michael M.
• Format: Dataset
• Language: English
• Published: Dryad 2022
• Subjects: FOS Biological sciences; Adaptive processes; Anguilla anguilla; Epigenetics; hox clusters; Hybridization; Methylation; Subarctic
• Online Access: https://dx.doi.org/10.5061/dryad.q2bvq83nm; https://datadryad.org/stash/dataset/doi:10.5061/dryad.q2bvq83nm

The role of methylation in adaptive, developmental and speciation processes has attracted considerable interest, but interpretation of results is complicated by diffuse boundaries between genetic and non-genetic variation. We studied whole genome genetic and methylation variation in the European eel, distributed from subarctic to subtropical environments, but with panmixia precluding genetically based local adaptation beyond single-generation responses. Overall methylation was 70.9%, with hypomethylation predominantly found in promoters and first exons. Redundancy analyses involving juvenile glass eels showed 0.06% and 0.03% of the variance at SNPs to be explained by localities and environmental variables, respectively, with GO terms of genes associated with outliers primarily involving neural system functioning. For CpGs 2.98% and 1.36% of variance was explained by localities and environmental variables. Differentially methylated regions particularly included genes involved in developmental processes, with ...