Genome-wide methylation in the panmictic European eel (Anguilla anguilla) ...

The role of methylation in adaptive, developmental and speciation processes has attracted considerable interest, but interpretation of results is complicated by diffuse boundaries between genetic and non-genetic variation. We studied whole genome genetic and methylation variation in the European eel...

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Bibliographic Details
Main Authors: Liu, Shenglin, Tengstedt, Aja Noersgaard Buur, Jacobsen, Magnus W., Pujolar, Jose Martin, Jónsson, Bjarni, Lobón-Cervià, Javier, Bernatchez, Louis, Hansen, Michael M.
Format: Dataset
Language:English
Published: Dryad 2022
Subjects:
FOS Biological sciences
Adaptive processes
Anguilla anguilla
Epigenetics
hox clusters
Hybridization
Methylation
Subarctic
Online Access:https://dx.doi.org/10.5061/dryad.q2bvq83nm
https://datadryad.org/stash/dataset/doi:10.5061/dryad.q2bvq83nm
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Summary:The role of methylation in adaptive, developmental and speciation processes has attracted considerable interest, but interpretation of results is complicated by diffuse boundaries between genetic and non-genetic variation. We studied whole genome genetic and methylation variation in the European eel, distributed from subarctic to subtropical environments, but with panmixia precluding genetically based local adaptation beyond single-generation responses. Overall methylation was 70.9%, with hypomethylation predominantly found in promoters and first exons. Redundancy analyses involving juvenile glass eels showed 0.06% and 0.03% of the variance at SNPs to be explained by localities and environmental variables, respectively, with GO terms of genes associated with outliers primarily involving neural system functioning. For CpGs 2.98% and 1.36% of variance was explained by localities and environmental variables. Differentially methylated regions particularly included genes involved in developmental processes, with ...

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