Data from: Genetic rescue of an endangered domestic animal through outcrossing with closely related breeds: a case study of the Norwegian Lundehund ...

• Main Authors: Stronen, Astrid V., Salmela, Elina, Baldursdóttir, BK, Berg, P, Espelien, IS, Järvi, Kirsi, Jensen, Henrik, Kristensen, TN, Melis, Claudia, Manenti, Tommaso, Lohi, Hannes, Pertoldi, Cino, Kristensen, Torsten N.
• Format: Dataset
• Language: English
• Published: Dryad 2017
• Subjects: outlier loci; Canis lupus familiaris; single nucleotide polymorphism; Inbreeding; Canis lupus
• Online Access: https://dx.doi.org/10.5061/dryad.5gm12; https://datadryad.org/stash/dataset/doi:10.5061/dryad.5gm12

Genetic rescue, outcrossing with individuals from a related population, is used to augment genetic diversity in populations threatened by severe inbreeding and extinction. The endangered Norwegian Lundehund dog (henceforth Lundehund) underwent at least two severe bottlenecks in the 1940s and 1960s that each left only five inbred dogs, and the approximately 1500 dogs remaining world-wide today appear to descend from only two individuals. The Lundehund has a high prevalence of a gastrointestinal disease, to which all remaining dogs may be predisposed. Outcrossing is currently performed with three Nordic Spitz breeds: Norwegian Buhund, Icelandic Sheepdog, and Norrbottenspets. Examination of single nucleotide polymorphism (SNP) genotypes based on 165K loci in 48 dogs from the four breeds revealed substantially lower genetic diversity for the Lundehund (HE 0.035) than for other breeds (HE 0.209-0.284). Analyses of genetic structure with 16K linkage disequilibrium-pruned SNPs showed four distinct genetic clusters. ... : NordicDogs_IDExcel file with list of individuals and dog breeds: NordicDogs_ID.xlsxNordicDogs_4mars2014PED file with individual data: NordicDogs_4mars2014.pedNordicDogs_4mars2014MAP file with data on genetic markers: NordicDogs_4mars2014.map ...