Amoebic gill disease of Atlantic salmon : resistance, serum antibody response and factors that may influence disease severity ...
Amoebic gill disease (AGD) is a condition of some marine-cultured fish worldwide and is the result of Neoparamoeba spp. infection. If AGD-affected fish are left untreated, major mortalities can occur. In Tasmania, Australia, fresh water bathing remains the only treatment for AGD, a practice that rep...
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| Format: | Thesis |
| Language: | unknown |
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University Of Tasmania
2023
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| Online Access: | https://dx.doi.org/10.25959/23251028.v1 https://figshare.utas.edu.au/articles/thesis/Amoebic_gill_disease_of_Atlantic_salmon_resistance_serum_antibody_response_and_factors_that_may_influence_disease_severity/23251028/1 |
| Summary: | Amoebic gill disease (AGD) is a condition of some marine-cultured fish worldwide and is the result of Neoparamoeba spp. infection. If AGD-affected fish are left untreated, major mortalities can occur. In Tasmania, Australia, fresh water bathing remains the only treatment for AGD, a practice that represents approximately 10-20% of production costs. Therefore, development of a preventative measure such as vaccination is a priority for Tasmanian salmon growers. In this project, resistance of Atlantic salmon to AGD and the development of a serum antibody response to Neoparamoeba spp. were assessed. Sera from AGD-affected Atlantic salmon were screened to identify potential candidate antigens for an AGD vaccine. Atlantic salmon exposed to Neoparamoeba spp. and subsequently challenged with AGD demonstrated resistance in terms of increased survival compared to AGD-narve fish. In addition, antibodies that bound cell-surface carbohydrate epitope(s) of Neoparamoeba spp. were detected in the sera of some fish after ... |
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