Evaluation of immersion immunisation of Atlantic salmon (Salmo salar) against yersiniosis ...

Yersinia ruckeri, a Gram-negative bacteria, is a pathogen which causes yersiniosis and significant losses in farmed Atlantic salmon (Salmo salar) in the Southern Hemisphere. Currently, Yersinivac-B, prepared from formalin killed whole-cells, is a commercial bacterin-based vaccine manufactured by MSD...

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Bibliographic Details
Main Author: Nguyen, TD
Format: Thesis
Language:unknown
Published: University Of Tasmania 2023
Subjects:
Online Access:https://dx.doi.org/10.25959/23240108
https://figshare.utas.edu.au/articles/thesis/Evaluation_of_immersion_immunisation_of_Atlantic_salmon_Salmo_salar_against_yersiniosis/23240108
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Summary:Yersinia ruckeri, a Gram-negative bacteria, is a pathogen which causes yersiniosis and significant losses in farmed Atlantic salmon (Salmo salar) in the Southern Hemisphere. Currently, Yersinivac-B, prepared from formalin killed whole-cells, is a commercial bacterin-based vaccine manufactured by MSD Animal Health. It is delivered by bath immersion vaccination against Y. ruckeri for most Tasmanian Atlantic salmon. Signifi-cant mortality events may still occur despite vaccination. This thesis focused on the improvement of yersiniosis vaccine efficacy for Atlantic salmon by using different administrated methods of immersion immunisation. The following aims were addressed in this thesis: ‚Äö Evaluate the effects of different inactivation methods of Y. ruckeri on the effica-cy of single dip vaccines including formalin inactivation, ammonium sulphate inactivation, and pH-lysed then formalin treated inactivation. ‚Äö Compare hyperosmotic pretreatment with direct immersion in Atlantic salmon (Salmo salar) by using ...