A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina ...
A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate ( 1 ) and 4 known compounds ( 2 - 5 ) were isolated from the Antarctic lichen, Pertusaria dactylina ( Pertusariaceae ). The structure of the new compound was determined by means of One-dimensional and two dimen...
| Main Authors: | , , , , , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | unknown |
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SAGE Journals
2020
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| Subjects: | |
| Online Access: | https://dx.doi.org/10.25384/sage.c.4893264 https://sage.figshare.com/collections/A_New_Chlorinated_Phenolic_Compound_From_the_Antarctic_Lichen_i_Pertusaria_dactylina_i_/4893264 |
| Summary: | A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate ( 1 ) and 4 known compounds ( 2 - 5 ) were isolated from the Antarctic lichen, Pertusaria dactylina ( Pertusariaceae ). The structure of the new compound was determined by means of One-dimensional and two dimensional nuclear magnetic resonance (1D and 2D NMR) and high-resolution fast atom bombardment mass spectrometry (HRFABMS) experiments. The antimicrobial activities of compounds 1 to 5 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC 50 value of 67 ± 7 μg/mL. ... |
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