Assessing the efficacy of a novel galactooligosaccharide to promote fish health and robustness ...

Aquaculture has been steadily increasing global production; however, there remains a progressively greater demand for sustainable sources of protein, whilst the prevalence of disease represents a major constraint to industry growth. Feed additives are gaining traction as useful tools to help combat...

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Bibliographic Details
Main Author: Sykes, Lucy May
Format: Text
Language:English
Published: University of Plymouth 2023
Subjects:
GOS
PhD
Online Access:https://dx.doi.org/10.24382/2666
https://pearl.plymouth.ac.uk/bms-theses/31
Description
Summary:Aquaculture has been steadily increasing global production; however, there remains a progressively greater demand for sustainable sources of protein, whilst the prevalence of disease represents a major constraint to industry growth. Feed additives are gaining traction as useful tools to help combat disease and promote health, and previous research has documented benefits to the mucosal surfaces and microbial communities within a range of teleost species. Three experimental in vivo feeding trials were undertaken using a range of in-depth analyses, such as growth performance, haematology, immunology, intestinal histology, intestinal gene expression and intestinal bacterial 16S rRNA sequence libraries. Studies were conducted on three important aquaculture species: rainbow trout (Oncorhynchus mykiss), Atlantic salmon (Salmo salar) and Nile tilapia (Oreochromis niloticus). All three experiments revealed that dietary B-GOSĀ® applications modulated the intestinal bacterial communities and intestinal gene expression. ...