The latent tuberculosis infection cascade of care in Iqaluit, Nunavut, 2012–2016 ...

Abstract Background A remote arctic region of Canada predominantly populated by Inuit with the country’s highest incidence of tuberculosis. Methods The study was undertaken to describe the latent tuberculosis infection (LTBI) cascade of care and identify factors associated with non-initiation and no...

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Bibliographic Details
Main Authors: Pease, Christopher, Zwerling, Alice, Mallick, Ranjeeta, Patterson, Mike, Demaio, Patricia, Finn, Sandy, Allen, Jean, Van Dyk, Deborah, Alvarez, Gonzalo G
Format: Article in Journal/Newspaper
Language:English
Published: My University 2019
Subjects:
Online Access:https://dx.doi.org/10.20381/ruor-24011
https://ruor.uottawa.ca/handle/10393/39768
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Summary:Abstract Background A remote arctic region of Canada predominantly populated by Inuit with the country’s highest incidence of tuberculosis. Methods The study was undertaken to describe the latent tuberculosis infection (LTBI) cascade of care and identify factors associated with non-initiation and non-completion of LTBI treatment. Data were extracted retrospectively from medical records for all patients with a tuberculin skin test (TST) implanted in Iqaluit, Nunavut between January 2012 and March 2016. Associations between demographic and clinical factors and both treatment non-initiation among and treatment non-completion were identified using log binomial regression models where convergence could be obtained and Poisson models with robust error variance where convergence was not obtained. Results Of 2303 patients tested, 439 (19.1%) were diagnosed with LTBI. Treatment was offered to 328 patients, was initiated by 246 (75.0% of those offered) and was completed by 186 (75.6% of initiators). In multivariable ...