Smokin' hot: adolescent smoking and the risk of psychosis. ...

OBJECTIVE: Daily smoking has been associated with a greater risk of psychosis. However, we are still lacking studies to adjust for baseline psychotic experiences and other substance use. We examined associations between daily smoking and psychosis risk in a 15-year follow-up while accounting for the...

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Bibliographic Details
Main Authors: Mustonen, A, Ahokas, T, Nordström, T, Murray, GK, Mäki, P, Jääskeläinen, E, Heiskala, A, Mcgrath, JJ, Scott, JG, Miettunen, J, Niemelä, S
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2018
Subjects:
epidemiology
nicotine
psychosis
schizophrenia
tobacco
Adolescent
Adolescent Behavior
Adult
Cigarette Smoking
Female
Finland
Follow-Up Studies
Humans
Male
Psychotic Disorders
Northern Finland
Online Access:https://dx.doi.org/10.17863/cam.22971
https://www.repository.cam.ac.uk/handle/1810/275706
Description
Summary:OBJECTIVE: Daily smoking has been associated with a greater risk of psychosis. However, we are still lacking studies to adjust for baseline psychotic experiences and other substance use. We examined associations between daily smoking and psychosis risk in a 15-year follow-up while accounting for these covariates in a prospective sample (N = 6081) from the Northern Finland Birth Cohort 1986. METHODS: Self-report questionnaires on psychotic experiences (PROD-screen), tobacco smoking and other substance use were completed when the cohort members were 15-16 years old. Tobacco smoking was categorized into three groups (non-smokers, 1-9 cigarettes and ≥10 cigarettes/day). Psychosis diagnoses were obtained from national registers until the age of 30 years. RESULTS: Subjects in heaviest smoking category were at increased risk of subsequent psychosis (unadjusted HR = 3.15; 95% CI 1.94-5.13). When adjusted for baseline psychotic experiences the association persisted (HR = 2.87; 1.76-4.68) and remained significant even ...

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