Detection of a Yersinia pestis gene homologue in rodent samples

A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. S...

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Bibliographic Details
Main Authors: Giles, Timothy A., Greenwood, Alex D., Tsangaras, Kyriakos, Giles, Tom C., Barrow, Paul A., Hannant, Duncan, Abu-Median, Abu-Bakr, Yon, Lisa
Format: Article in Journal/Newspaper
Language:unknown
Published: Freie Universität Berlin 2016
Subjects:
Genetics
FOS Biological sciences
Microbiology
Molecular Biology
500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie576 Genetik und Evolution
500 Naturwissenschaften und Mathematik570 Biowissenschaften; Biologie570 Biowissenschaften; Biologie
Canada
Rattus rattus
Online Access:https://dx.doi.org/10.17169/refubium-21158
https://refubium.fu-berlin.de/handle/fub188/16978
Description
Summary:A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker.

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