(Table 1) Characteristics of South Pole personnel according to forced expiratory flow (FEF25-75) response to altitude ...

The impact of acute altitude exposure on pulmonary function is variable. A large inter-individual variability in the changes in forced expiratory flows (FEFs) is reported with acute exposure to altitude, which is suggested to represent an interaction between several factors influencing bronchial ton...

Full description

Bibliographic Details
Main Authors: Lalande, Sophie, Anderson, P J, Miller, A D, Ceridon, M L, Beck, K C, O'Malley, K A, Johnson, J B, Johnson, B D
Format: Dataset
Language:English
Published: PANGAEA 2011
Subjects:
IPY
Online Access:https://dx.doi.org/10.1594/pangaea.815165
https://doi.pangaea.de/10.1594/PANGAEA.815165
Description
Summary:The impact of acute altitude exposure on pulmonary function is variable. A large inter-individual variability in the changes in forced expiratory flows (FEFs) is reported with acute exposure to altitude, which is suggested to represent an interaction between several factors influencing bronchial tone such as changes in gas density, catecholamine stimulation, and mild interstitial edema. This study examined the association between FEF variability, acute mountain sickness (AMS) and various blood markers affecting bronchial tone (endothelin-1, vascular endothelial growth factor (VEGF), catecholamines, angiotensin II) in 102 individuals rapidly transported to the South Pole (2835 m). The mean FEF between 25 and 75% (FEF25-75) and blood markers were recorded at sea level and after the second night at altitude. AMS was assessed using Lake Louise questionnaires. FEF25-75 increased by an average of 12% with changes ranging from -26 to +59% from sea level to altitude. On the second day, AMS incidence was 36% and was ... : Data extracted in the frame of a joint ICSTI/PANGAEA IPY effort, see http://doi.pangaea.de/10.1594/PANGAEA.150150 ...