The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ...
Background Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. VHSV isolates are classified into four genotypes and each group is endemic to specific geographic...
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ftdatacite:10.13016/m2vpol-5ltb 2023-08-27T04:10:53+02:00 The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... Yusuff, Shamila Kurath, Gael Sun Kim, Min Tesfaye, Tarin M. Li, Jie McKenney, Douglas G. Vakharia, Vikram N. 2019 https://dx.doi.org/10.13016/m2vpol-5ltb http://mdsoar.org/handle/11603/13128 en eng BioMed Central Ltd Creative Commons Attribution 4.0 International Attribution 4.0 International (CC BY 4.0) This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 viral hemorrhagic septicemia virus VHSV virulence determinant fish rhabdovirus glycoprotein non-virion protein polymerase protein CreativeWork article 2019 ftdatacite https://doi.org/10.13016/m2vpol-5ltb 2023-08-07T14:24:23Z Background Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. VHSV isolates are classified into four genotypes and each group is endemic to specific geographic regions in the north Atlantic and Pacific Oceans. Most viruses in the European VHSV genotype Ia are highly virulent for rainbow trout (Oncorhynchus mykiss), whereas, VHSV genotype IVb viruses from the Great Lakes region in the United States, which caused high mortality in wild freshwater fish species, are avirulent for trout. This study describes molecular characterization and construction of an infectious clone of the virulent VHSV-Ia strain DK-3592B from Denmark, and application of the clone in reverse genetics to investigate the role of selected VHSV protein(s) in host-specific virulence in rainbow trout (referred to as trout-virulence). Methods Overlapping cDNA fragments of the DK-3592B genome were cloned ... Article in Journal/Newspaper North Atlantic DataCite Metadata Store (German National Library of Science and Technology) Pacific |
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DataCite Metadata Store (German National Library of Science and Technology) |
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language |
English |
topic |
viral hemorrhagic septicemia virus VHSV virulence determinant fish rhabdovirus glycoprotein non-virion protein polymerase protein |
spellingShingle |
viral hemorrhagic septicemia virus VHSV virulence determinant fish rhabdovirus glycoprotein non-virion protein polymerase protein Yusuff, Shamila Kurath, Gael Sun Kim, Min Tesfaye, Tarin M. Li, Jie McKenney, Douglas G. Vakharia, Vikram N. The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
topic_facet |
viral hemorrhagic septicemia virus VHSV virulence determinant fish rhabdovirus glycoprotein non-virion protein polymerase protein |
description |
Background Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. VHSV isolates are classified into four genotypes and each group is endemic to specific geographic regions in the north Atlantic and Pacific Oceans. Most viruses in the European VHSV genotype Ia are highly virulent for rainbow trout (Oncorhynchus mykiss), whereas, VHSV genotype IVb viruses from the Great Lakes region in the United States, which caused high mortality in wild freshwater fish species, are avirulent for trout. This study describes molecular characterization and construction of an infectious clone of the virulent VHSV-Ia strain DK-3592B from Denmark, and application of the clone in reverse genetics to investigate the role of selected VHSV protein(s) in host-specific virulence in rainbow trout (referred to as trout-virulence). Methods Overlapping cDNA fragments of the DK-3592B genome were cloned ... |
format |
Article in Journal/Newspaper |
author |
Yusuff, Shamila Kurath, Gael Sun Kim, Min Tesfaye, Tarin M. Li, Jie McKenney, Douglas G. Vakharia, Vikram N. |
author_facet |
Yusuff, Shamila Kurath, Gael Sun Kim, Min Tesfaye, Tarin M. Li, Jie McKenney, Douglas G. Vakharia, Vikram N. |
author_sort |
Yusuff, Shamila |
title |
The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
title_short |
The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
title_full |
The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
title_fullStr |
The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
title_full_unstemmed |
The glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
title_sort |
glycoprotein, non-virion protein, and polymerase of viral hemorrhagic septicemia virus are not determinants of host-specific virulence in rainbow trout ... |
publisher |
BioMed Central Ltd |
publishDate |
2019 |
url |
https://dx.doi.org/10.13016/m2vpol-5ltb http://mdsoar.org/handle/11603/13128 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
North Atlantic |
genre_facet |
North Atlantic |
op_rights |
Creative Commons Attribution 4.0 International Attribution 4.0 International (CC BY 4.0) This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. https://creativecommons.org/licenses/by/4.0/legalcode cc-by-4.0 |
op_doi |
https://doi.org/10.13016/m2vpol-5ltb |
_version_ |
1775353253854183424 |