Age-dependent gene expression in the inner ear of big brown bats (Eptesicus fuscus) ...
Funding for Open Access provided by the UMD Libraries' Open Access Publishing Fund. ... : For echolocating bats, hearing is essential for survival. Specializations for detecting and processing high frequency sounds are apparent throughout their auditory systems. Recent studies on echolocating m...
| Main Authors: | , , |
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| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Digital Repository at the University of Maryland
2017
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| Online Access: | https://dx.doi.org/10.13016/m2610vv88 http://drum.lib.umd.edu/handle/1903/20690 |
| Summary: | Funding for Open Access provided by the UMD Libraries' Open Access Publishing Fund. ... : For echolocating bats, hearing is essential for survival. Specializations for detecting and processing high frequency sounds are apparent throughout their auditory systems. Recent studies on echolocating mammals have reported evidence of parallel evolution in some hearing-related genes in which distantly related groups of echolocating animals (bats and toothed whales), cluster together in gene trees due to apparent amino acid convergence. However, molecular adaptations can occur not only in coding sequences, but also in the regulation of gene expression. The aim of this study was to examine the expression of hearingrelated genes in the inner ear of developing big brown bats, Eptesicus fuscus, during the period in which echolocation vocalizations increase dramatically in frequency. We found that seven genes were significantly upregulated in juveniles relative to adults, and that the expression of four genes through development correlated with estimated age. Compared to available data for mice, it appears that ... |
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