Retention of fatty acyl desaturase 1 (fads1) in elopomorpha and cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebrates

• Published in: BMC Evolutionary Biology
• Main Authors: Lopes-Marques, Mónica, Kabeya, Naoki, Qian, Yu, Ruivo, Raquel, Santos, Miguel M., Venkatesh, Byrappa, Tocher, Douglas R., Castro, L. Filipe C., Monroig, Óscar
• Other Authors: Fundação para a Ciência e a Tecnologia (Portugal), Ministério da Economia (Portugal), European Commission
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: BioMed Central 2018
• Subjects: Biosynthesis; Fatty acyl desaturase; Gene duplication; Gene loss; Long-chain polyunsaturated fatty acids; Arctic; Gar’
• Online Access: http://hdl.handle.net/10261/171299; https://doi.org/10.1186/s12862-018-1271-5; https://doi.org/10.13039/501100000780; https://doi.org/10.13039/501100001871

[Background] Provision of long-chain polyunsaturated fatty acids (LC-PUFA) in vertebrates occurs through the diet or via endogenous production from C18 precursors through consecutive elongations and desaturations. It has been postulated that the abundance of LC-PUFA in the marine environment has rem...