Compositions Derived from Modiolus Modiolus and Methods for Making and Using Same

Disclosed are compositions which include an isolated soft tissue from Modiolus modiolus (???MM???) and compositions which include an oil isolated from MM or a portion thereof. Also disclosed are methods of treating adenocarcinoma in a subject; methods of decreasing proliferation of adenocarcinoma ce...

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Bibliographic Details
Main Authors: Collin, Peter D., Adrian, Thomas E.
Format: Patent
Language:unknown
Published: United States Patent Office 2008
Subjects:
Online Access:http://hdl.handle.net/10504/68619
Description
Summary:Disclosed are compositions which include an isolated soft tissue from Modiolus modiolus (???MM???) and compositions which include an oil isolated from MM or a portion thereof. Also disclosed are methods of treating adenocarcinoma in a subject; methods of decreasing proliferation of adenocarcinoma cells, or of inducing apoptosis of adenocarcinoma cells, or of inducing differentiation of adenocarcinoma cells into non-cancerous cells; methods of inhibiting the activity of 5-lipoxygenase or 12-lipoxygenase or both in cells; and methods of treating a subject suffering from a disease or condition associated with excessive 5-lipoxygenase activity or 12-lipoxygenase activity or both. A process for preparing an MM extract by contacting MM or a portion thereof with a solvent under conditions effective to extract one or more materials from the MM or portion thereof is also described.