The importance of environment on respiratory genotype/phenotype relationships in the Inuit

Genetic and environmental influences and their interactions are central to asthma pathogenesis. This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in two geographically separated populations with common ancestry.

Bibliographic Details
Published in:Allergy
Main Authors: Candelaria, P V, Backer, V, Khoo, S-K, Bizzintino, J A, Hayden, C M, Baynam, G, Laing, I A, Zhang, G, Porsbjerg, C, Goldblatt, J, Le Souëf, P N
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Online Access:https://curis.ku.dk/portal/da/publications/the-importance-of-environment-on-respiratory-genotypephenotype-relationships-in-the-inuit(989adfd3-a323-40f5-a04d-2d14d5f9bc55).html
https://doi.org/10.1111/j.1398-9995.2009.02145.x
Description
Summary:Genetic and environmental influences and their interactions are central to asthma pathogenesis. This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in two geographically separated populations with common ancestry.