Detection of GSTM1, GSTT1 and the Ile105Val GSTP1 gene variants

We have developed a PCR multiplex method that in a fast, inexpensive and reliable manner can detect if a person has two, one or no GSTM1 and GSTT1 genes and which at the same time can detect the allelic status of the GSTP1 Ile105Val genetic variant. A total of 200 Danes, 100 Somalis and 100 Greenlan...

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Bibliographic Details
Main Authors: Buchard, Anders, Sanchez, Juan J., Dalhoff, Kim, Morling, Niels
Format: Other Non-Article Part of Journal/Newspaper
Language:English
Published: Elsevier 2008
Subjects:
greenlander*
Online Access:https://curis.ku.dk/portal/da/publications/detection-of-gstm1-gstt1-and-the-ile105val-gstp1-gene-variants(7db7fb50-a201-11de-bc73-000ea68e967b).html
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Summary:We have developed a PCR multiplex method that in a fast, inexpensive and reliable manner can detect if a person has two, one or no GSTM1 and GSTT1 genes and which at the same time can detect the allelic status of the GSTP1 Ile105Val genetic variant. A total of 200 Danes, 100 Somalis and 100 Greenlanders were genotyped. This multiplex PCR assay enables future large-scale studies to investigate the role of GSTs

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